Neuro-Oncology Program
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MSCTR | Cancer Research |Translational Research
liomas, the most common form of brain tumors of the adult CNS, originate from neuroepithelial tissue and are classified morphologically as astrocytic, oligodendroglial, ependymal, and choroid plexus tumors. Glioblastoma multiforme (grade IV astrocytoma; GBM) is one of the most aggressive forms of brain tumors and a primary area of focus for the Neurooncology Group at MSCTR.
“The broad aims of the Neuro-Oncology Program are:”
We envision implementation of the two arms in parallel, through a multi-disciplinary team effort, involving basic scientists with expertise in high throughput technologies, cell biologists, clinicians and informaticians. Embedded in these efforts will be the mission of mentoring young clinicians and research scientists who will lead MSCTR both as independent scientists and as a well-coordinated team directed towards improved neuro oncology practices. This will ensure continued institutional efforts. Gliomas, particularly Glioblastoma, are one of the most targeted tumors in clinical oncology research globally. Hence, the center will aim for networking with other national and international clinical centers in our efforts to formulate pioneering treatment models for malignant Glioblastoma.
ravisirdeshmukh@gmail.com
Project: Dr. Ravi Sirdeshmukhholds a joint appointment as Principal Advisor, Neuro-oncology Research at MSCTR. His research interests span in the areas of protein and nucleic acid biochemistry and his earlier work included RNA processing, mRNA stability, structure-function relationship of ‘ribonucleases’ and their regulation. More recently his interests have been in the areas of Proteomics of gliomas – a major class of brain tumors and Head & Neck cancers. He has trained and mentored a number of young associates, Ph.D. students and post-doctoral fellows. At MSCTR, he is spearheading translational research programs in brain tumors.
Research Scientist sujan.dhar@ms-mf.org
Project: Dr. Sujan K Dhar (PhD in Theoretical Physics from Indian Institute of Science) heads the newly formed computation Biology program at MSCTR, MSMF. Following his passion in computation, Dr Dhar started his career as a scientist in the Supercomputer Education and Research Center (SERC) at IISc before joining the software and then the pharma-support Industry. As an entrepreneur in the pharma-support Induatry, he started working with the clinicians and got back to his initial passion of computation, now with a clinically relevant translational focus.
Research Scientist atanu@ms-mf.org
Project:
Dr. Atanu Ghorai, Ph.D. is a Senior Research Scientist in the Neuro-Oncology Program at the Mazumdar Shaw Center for Translational Research (MSCTR), where he leads efforts to address therapeutic resistance in glioblastoma. His research integrates multi-omics with cellular and molecular approaches to uncover mechanisms driving tumor progression and poor treatment response, with the goal of identifying clinically actionable targets.
Dr. Ghorai obtained his Ph.D. in Biophysics from the University of Kalyani, where his work investigated the cellular role of PARP-1 in DNA damage response, repair, and apoptosis following radiation exposure. His doctoral research specifically compared high-linear energy transfer (LET) radiation (carbon-ion/charged-particle therapy) with low-LET gamma radiation in cancer cell lines.
Project Associate I rakshitha@ms-mf.org
Project: Development of a Human iPSC-Derived Midbrain Assembloid Model to Study Parkinson’s Disease; Development of Glioma Patient-derived Cellular Models that Capture Tumorigenic Features & Chemo-response.
Junior Research Fellow gnana.ajay@ms-mf.org
Project: Development of Glioma Patient-derived Cellular Models that Capture Tumorigenic Features & Chemo-response. Development of a Human iPSC-Derived Midbrain Assembloid Model to Study Parkinson’s Disease. Cloning, expression, and cellular characterization of gpcr56 N-terminus and TG2
Junior Research Fellow vijina@ms-mf.org
Hari P.S
Senior Research Fellow
Yogesh Pasupathy
Project Assistant
Anurag C N
Project Assistant
Chaitanya Kotyada
Senior Research Fellow
Dr. Lavanya Balakrishnan
Post Doctoral Fellow
Dr. Shivkumar B.M
Research Scientist
Manasa Ogeti
Junior Research Fellow
Chaitra B Ramesh
Project Assistant
Azin Zabihi
Junior Research Fellow
Dr. Arivusudar Everad John
Research Scientist
Raksha Ganesh
Senior Research Fellow
Pranali Sonpatki
Senior Research Fellow
Divya Naik
Senior Research Fellow
Darshat Shah
Senior Research Fellow
athijit Mallick
Junior Research Fellow
Dr Nameeta Shah
Principal Investigator
Gouri Raj
(MSc) Junior Research Fellow
Gaurav Sahoo
(MSc) Junior Research Fellow
Athira K
Junior Research Fellow